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Three-Component Domino Reaction Using the Bestmann Ohira Reagent: A Regioselective Synthesis of Phosphonyl Pyrazole
No one who has given even a passing glance to the literature of organic chemistry will have failed to note a flourishing development of step-economic reactions that achieve multiple bond formations in one operation. In this context, multicomponent reaction (MCR) processes usually satisfy most criteria (readily available starting reagents, atom-economical, environ - mentally friendly, etc.) required for ideal organic syntheses. Undoubtedly, such reactions offer an efficient way to generate complex molecular frameworks due to their inherent convergence and complexity-generating ability.
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