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Guide

E22: Synthesis of Peptides and Peptidomimetics

5 English-language volumes

Editor-in-Chief:
Murray Goodman, San Diego, USA

Editors:
Arthur Felix, Mahwah, USA
Luis Moroder, Martinsried, Germany
Claudio Toniolo, Padova, Italy

Houben-Weyl Synthesis of Peptides and Peptidomimetics is to represent the most valuable extract from more than 100 years of peptide synthesis, first reported by Emil Fischer in 1899. In 1974, Houben-Weyl published Synthese von Peptiden edited by Professor Erich Wünsch. This field of chemistry has changed dramatically since then and the new English language volume will reflect the current challenges of a discipline which is at the center of modern chemistry and biology.

The five-volume set, edited by the internationally renowned peptide chemists Professors Murray Goodman, Arthur Felix, Luis Moroder, and Claudio Toniolo will comprise a critical selection of synthetic methods in a consistent style, and will be indispensable for every synthetic chemist.

Synthesis of Peptides (E22a and E22b) includes protecting groups, peptide bond formation, the synthesis of peptides and proteins detailing general and specific methods, and analytical techniques used to determine the structure and composition of peptides.

Synthesis of Peptidomimetics (E22c and E22d) features side and/or main-chain modified peptides, peptides with secondary structure mimetics and inducers, de novo peptide structures, macropeptide structures, and reactive peptides.

Reviewer's comments on E22a:

"...In this first volume, you will find many synthetic gems that you can bring to your own practice of peptide or peptidomimetic chemistry, whether you are new to the field or an old-timer. This is a volume that you will want to explore; once you start you will have trouble putting it down." - Victor J. Hruby, Arizona, USA.

Click here to read an independent review (pdf) of E22a by Dr. John Jones.

Click here for a detailed table of contents (pdf) for volumes E22.

Vol.	Pub. Year	No. of Pages	Price	ISBN (RoW) ISBN (US)
E22a	2002	976	€uro 1850 US$ 2200	3-13-219604-5 1-58890-022-3	order
E22b	2002	785	€uro 1850 US$ 2200	3-13-114424-6 1-58890-023-1	order
E22c	2002	847	€uro 2200 US$ 2640	3-13-125514-5 1-58890-024-X	order
E22d	2003	395	€uro 2200 US$ 2640	3-13-128874-4 1-58890-070-3	order
E22e	2003	497	€uro 1400 US$ 1680	3-13-136394-0 1-58890-182-3	order

For further information or to receive a free Houben-Weyl Users' Guide please contact us.

News

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Pharmaceutical Substances 3.1

was released on October 28th, 2008. This release features 51 new active pharmaceutical ingredients and updates to 16 syntheses.

Pharmaceutical Substances

The 5th edition of Pharmaceutical Substances is now available in hardcover format. Click here for more info and to order a personal copy.

Over 20,000
New Reactions

Science of Synthesis 3.6 is now available and contains 38 volumes with a total of 215,000 reactions. More details on the newly released version 3.6.

Award for
Barry M. Trost

We would like to congratulate Barry M. Trost, Editorial Board Member, Science of Synthesis, on being awarded the Nagoya Gold Medal of Organic Chemistry 2008.

Award for
Eric N. Jacobsen

We would like to congratulate Eric N. Jacobsen, Editorial Board Member, Science of Synthesis, on being awarded the Yamada–Koga Prize 2008 which will be awarded on November 14, 2008, at the 18th Symposium on Optically Active Compounds held in Tokyo, Japan.

Awards for
Steven V. Ley

We would like to congratulate Steven V. Ley, Editorial Board Member, Science of Synthesis, on receiving the Prous Institute-Overton and Meyer Award and the Hans Herloff Inhoffen Medal.

Volume Publication

We are pleased to announce the publication of Science of Synthesis Volume 37 [Ethers] by Craig J. Forsyth and Eric N. Jacobsen in May 2008.

Professor
John Colin Tatlow
(1923–2008)

We are very sorry to announce that Professor John Colin Tatlow passed away on April 9th, 2008. Professor Tatlow was the Editor-in-Chief of the E10 Organo-Fluorine Compounds (Houben–Weyl) series and made a major contribution to fluorine chemistry during his career. He was the recipient of the American Chemical Society Award for Creative Work in Fluorine Chemistry in 1990. We would like to extend our sincere condolences to his family and friends.

Thieme IUPAC Prize

Congratulations to
F. Dean Toste, recipient of the 2008 Thieme–IUPAC Prize.